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George E. Palade

George E. PaladeAKA George Emil Palade

Born: 19-Nov-1912
Birthplace: Jassy (Iasi), Romania
Died: 7-Oct-2008
Location of death: Del Mar, CA
Cause of death: Illness

Gender: Male
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Scientist, Doctor
Party Affiliation: Democratic

Nationality: United States
Executive summary: Microstructure of the cell

Military service: Romanian Army Medical Corps (1942-45)

George E. Palade mapped the structure of mitochondria, and showed that microsomes (which had previously been thought to be mitochondria fragments) are parts of the internal cellular transport system. He studied and described cytoplasm (ribosomes), investigated chemical synapses, and developed better methods for centrifuging, electron microscopy, and preparation of tissue for lab work. He won the Nobel Prize for Medicine or Physiology in 1974 (with Albert Claude and Christian de Duve), for their separate studies of the metabolism of organelles in biological cells.

While he was at Rockefeller University, Palade worked under two Nobel laureates, first Albert Claude and later Herbert S. Gasser. He spent more than a decade editing the scientific review Journal of Biophysical and Biochemical Cytology. His wife, Marilyn Gist Farquhar, was a professor of cellular and molecular medicine at the University of California at San Diego, and a past president of the American Society for Cell Biology. His son, Philip Palade, is a pharmacology professor at the University of Arkansas.

Father: Emil Palade (philosophy professor)
Mother: Constanta Cantemir-Palade (school teacher)
Sister: Adriana Palade (history professor)
Sister: Constanta Palade (physician)
Wife: Irina Malaxa (m. 1941, d. 1969)
Daughter: Georgia Palade Van Duzen (real estate broker)
Son: Philip Palade (pharmacology professor)
Wife: Marilyn Gist Farquhar (professor of cellular and molecular medicine, m. 1970)

    High School: Al Hasdeu Lyceum, Buzau, Romania (1930)
    Medical School: MD, University of Bucharest (1940)
    Teacher: Clinical Medicine, University of Bucharest (1941-46)
    Scholar: Biology, New York University (1946)
    Scholar: Biology, Rockefeller University (1946-58)
    Professor: Cytology, Rockefeller University (1958-72)
    Professor: Pathology and Clinical Medicine, Yale School of Medicine (1972-90)
    Professor: Cellular and Molecular Medicine, University of California at San Diego (1990-)
    Administrator: Dean for Scientific Affairs, University of California at San Diego (1990-)

    Lasker Award 1966
    Nobel Prize for Medicine 1974 (with Albert Claude and Christian de Duve)
    National Medal of Science 1986
    American Academy of Arts and Sciences
    Democratic Congressional Campaign Committee
    Democratic Senatorial Campaign Committee
    Gephardt for President
    Gore 2000
    National Academy of Sciences
    Pontifical Academy of Sciences
    Naturalized US Citizen 1952
    Romanian Ancestry
    Risk Factors: Parkinson's

Official Website:

Author of books:
Major Basic Research Discoveries (1991)
Cell Biology: Basic Research and Applications (1986, with Walter G Rosen)

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