William S. Knowles AKA William Standish Knowles Born: 1-Jun-1917 Birthplace: Taunton, MA Died: 13-Jun-2012 Location of death: Chesterfield, MO Cause of death: unspecified Remains: Cremated
Gender: Male Race or Ethnicity: White Sexual orientation: Straight Occupation: Chemist Nationality: United States Executive summary: Chiral catalysts American chemist William S. Knowles won the Nobel Prize in 2000, for his research into chirally catalysed hydrogenation reactions. His work allowed the development of catalysts for chemical reactions designed to trigger formation of high concentrations of a particular form of a molecule, while producing only small quantities of the molecule's mirror image. This led to the design of chiral catalysts for hydrogenation reactions, culminating in a process for mass production of L-3,4-dihydroxyphenylalanine (L-DOPA), a drug used in the treatment of Parkinson disease. Father: George Bourne Knowles Mother: Alice Pierce Knowles Wife: Lesley Ann Cherbonnier ("Nancy", m. 1945, until his death, three daughters, one son) Daughter: Elizabeth Son: Peter Daughter: Lesley Daughter: Sarah
High School: Berkshire School, Berkshire, MA (1934) High School: Phillips Academy Andover (1935) University: Chemistry, Harvard University (1939) University: PhD, Columbia University (1942) Scholar: Steroids Research, Harvard University (1951-52)
ACS Award for Creative Invention 1982
ORCS Paul N. Rylander Award 1996
Nobel Prize for Chemistry 2001 (with Ryoji Noyori and K. Barry Sharpless) Monsanto Distinguished Science Fellow (1970-86)
Monsanto Senior Scientist (1966-70)
Monsanto Group Leader (1952-66)
Monsanto Research Chemist (1944-52)
Monsanto Research Chemist, Thomas and Hochwalt (1942-44)
Draft Deferment World War II
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