| Sandra Bullock | ... Annie |
| Jason Patric | ... Alex |
| Willem Dafoe | ... Geiger |
|
| Temuera Morrison | ... Juliano |
| Brian McCardie | ... Merced |
| Glenn Plummer | ... Maurice |
| Colleen Camp | ... Debbie |
| Lois Chiles | ... Celeste |
| Michael G. Hagerty | ... Harvey |
| Bo Svenson | ... Capt. Pollard |
| Francis Guinan | ... Rupert |
| Jeremy Hotz | ... Ashton |
| Royale Watkins | ... Dante |
| Christine Firkins | ... Drew |
| Tamia | ... Sheri |
| Kimmy Robertson | ... Liza (Cruise Director) |
| Patrika Darbo | ... Ruby |
| Connie Ray | ... Fran |
| Susan Barnes | ... Constance |
| Charles Parks | ... Frank |
|
| Enrique Murciano | ... Alejandro |
| Jessica Diz | ... Isabel |
| Alex Montesino | ... Control Room Chief Engineer |
| Mark Adair-Rios | ... Engine Room Crew Member #1 |
| Xavier Coronel | ... Engine Room Crew Member #2 |
| Tyler Patton | ... Engine Room Crew Member #3 |
| Craig A. Pinckes | ... Engine Room Crew Member #4 |
| Allison Dean | ... Marifa |
| Michael Robinson | ... Muster Deck Officer #1 |
| Joe D'Angerio | ... Muster Deck Officer #2 |
| Joe Foster | ... Pool Officer |
| Richard Speight, Jr. | ... "C" Deck Officer |
| Michael O'Hagan | ... Supertanker Captain |
| Christopher Wynne | ... Supertanker Officer #1 |
| Robert Herrick | ... Supertanker Officer #2 |
| Ivory Broome | ... Supertanker Crew Member #1 |
| Tim Conway | ... Mr. Kenter |
| Thomas J. Huff | ... Diaper Van Driver |
| Jay Lacopo | ... Real Estate Salesman |
| Alexander de Bont | ... Little Boy (Condo) |
| Kathryn Rossetter | ... Mother at Condo |
| Mark Beltzman | ... Convertible Owner |
| Mark Kriski | ... News Reporter |
| Ben Meyerson | ... Bridge Officer #1 |
| Ben Siegler | ... Policeman |
| Gustavo Laborie | ... Bridge Officer #2 |
| Jennifer S. Badger | ... Passenger #1 |
| Cheryl Bermeo | ... Passenger #2 |
| Jeff Brockton | ... Passenger #3 |
| Don Pulford | ... Passenger #4 |
| Cliff McLaughlin | ... Passenger #5 |
| Matthew Taylor | ... Passenger #6 |
| P. J. Wagner | ... Passenger #7 |
| May R. Boss | ... Passenger #8 |
| Nancy Collet | ... Passenger #9 |
| Wilma Edward | ... Woman on Phone |
