Peter Agre AKA Peter Courtland Agre Born: 30-Jan-1949 Birthplace: Northfield, MN
Gender: Male Religion: Lutheran Race or Ethnicity: White Sexual orientation: Straight Occupation: Biologist, Chemist Party Affiliation: Democratic Nationality: United States Executive summary: Water channels of cell membranes American hematologist Peter Agre (pronounced AHG-ray) won the Nobel Prize for Chemistry in 2003, for his 1991 discovery of aquaporins, proteins embedded in cell membranes that regulate and facilitate the flow of water molecules across and into cells, a process essential for life as we know it. Aquaporins form a channel in the membrane, allowing billions of water molecules to diffuse across the membrane every second, and serving as a river-like barrier to prevent other ions or molecules from crossing the channel. Agre has said that aquaporins are "the plumbing system for cells", and the potential applications of his discovery include the development of drugs to address brain edema following a stroke, fluid retention problems in heart disease, or virtually any other disease characterized by excess or inadequate fluids. Father: Courtland Agre (chemist) Mother: Ellen Swedberg Sister: Annetta (b. 1946) Brother: James (physician, b. 1950) Brother: Paul (mentally retarded) Sister: Ruth Brother: Mark (physician) Wife: Mary Macgill (m. 29-Mar-1975) Daughter: Sara (b. 1978) Daughter: Claire Daughter: Lydia (b. 1983, d. 21-Dec-1983) Son: Clarke (b. 1985)
High School: Theodore Roosevelt High School, Minneapolis, MN (night school, 1967) University: University of Minnesota (attended, 1967) University: BA Chemistry, Augsburg College (1970) Medical School: MD, Johns Hopkins University (1974) Scholar: Pharmacology, Johns Hopkins University (1974-75) Scholar: Internship, Case Western Reserve University (1975-78) Teacher: Hematology and Oncology, University of North Carolina at Chapel Hill (1978-81) Teacher: Biological Chemistry, Johns Hopkins University (1981-93) Professor: Biological Chemistry, Johns Hopkins University (1993-2005) Professor: Cell Biology, Duke University (2005-) Administrator: Vice Chancellor for Science and Technology, Duke University (2005-)
Eagle Scout 1964 Nobel Prize for Chemistry 2003 (with Roderick MacKinnon) Distinguished Eagle Scout Award Howard Hughes Medical Institute Scientific Review Board (2003-) Carnegie Institution for Science Embryology Lab (1988-89) Blood Editorial Board (1993-97)
Journal of Biological Chemistry Editorial Board (1999-2002)
Journal of Clinical Investigation Editorial Board (1993-)
Academy of Achievement 2004 American Academy of Arts and Sciences American Association for the Advancement of Science President (2009-10) American Philosophical Society American Physiological Society American Society for Biochemistry and Molecular Biology American Society for Cell Biology American Society for Clinical Investigation American Society of Hematology
American Society of Nephrology
Boy Scouts of America (childhood) Federation of American Scientists Board of Sponsors National Academy of Sciences 2000 Science Debate 2008 Scientists and Engineers for America Norwegian Ancestry Paternal and Maternal
Swedish Ancestry Maternal
Risk Factors: Hepatitis
Author of books:
Aquaporins (2001, chemistry; with Stefan Hohmann and Søren Nielsen)
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