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Linda B. Buck

Linda B. BuckBorn: 29-Jan-1947
Birthplace: Seattle, WA

Gender: Female
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Biologist

Nationality: United States
Executive summary: Odorant receptors and olfactory organization

American neurobiologist Linda B. Buck has studied how odors are perceived and identified. Her work has shown that the mammalian olfactory system senses a huge variety of structurally diverse chemicals in the external environment, mostly as odors, although certain chemical compounds such as pheromones and predator odors are not consciously smelled but more basically stimulate hormonal changes or instinctive behaviors.

With her colleague, Richard Axel, she cloned olfactory receptors in 1991, proving that smell-detectors are G protein-coupled receptors. In 1993 and 1994 she detailed the organization of odor receptor neurons in the nose, and in 2004 she and Axel shared the Nobel Prize for Medicine or Physiology for her research into the molecular mechanics of the sense of smell. She continues her works at the Fred Hutchinson Cancer Research Center in Seattle.

Father: (electrical engineer)
Mother: (homemaker)
Sister: (2 sisters)

    High School: Roosevelt High School, Seattle, WA (1965)
    University: BS Psychology, University of Washington (1975)
    University: BS Microbiology, University of Washington (1975)
    University: PhD Immunology, University of Texas at Dallas (1980)
    Fellow: Postdoctorate, Columbia University (1980-84)
    Teacher: Neurobiology, Harvard Medical School (1991-2001)
    Professor: Neurobiology, Harvard Medical School (2001-02)
    Teacher: Physiology and Biophysics, University of Washington (2002-)

    Takasago Award 1992
    Lewis S. Rosenstiel Award 1997
    Gairdner Foundation International Award 2003
    Nobel Prize for Medicine 2004 (with Richard Axel)
    American Academy of Arts and Sciences 2008
    American Association for the Advancement of Science 2002
    Fred Hutchinson Cancer Research Center (2002-)
    Howard Hughes Medical Institute Investigator (2001-)
    Howard Hughes Medical Institute Associate Investigator (1997-2000)
    Howard Hughes Medical Institute Ass't Investigator (1994-97)
    Howard Hughes Medical Institute Associate (1984-94)
    Alfred P. Sloan Foundation Fellowship, 1992
    Institute of Medicine 2006
    National Academy of Sciences 2003
    Irish Ancestry Paternal
    Swedish Ancestry Maternal

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