| Ethan Hawke | ... Hamlet |
|
| Kyle MacLachlan | ... Claudius |
| Diane Venora | ... Gertrude |
| Liev Schreiber | ... Laertes |
| Julia Stiles | ... Ophelia |
| Bill Murray | ... Polonius |
| Karl Geary | ... Horatio |
| Steve Zahn | ... Rosencrantz |
| Dechen Thurman | ... Guildenstern |
| Paula Malcomson | ... Marcella |
| Jeffrey Wright | ... Gravedigger |
| Rome Neal | ... Barnardo |
| Paul Bartel | ... Osric |
|
| and |
| Sam Shepard | ... Ghost |
|
| Casey Affleck | ... Fortinbras |
| Robert Thurman | ... Priest |
| Tim Blake Nelson | ... Flight Captain |
| John Martin | ... Claudius Bodyguard |
| Bernadette Jurkowski | ... Blockbuster Clerk |
| Robert MacNeil | ... Player King |
|
| Special Guest Appearances |
| D. J. Dara | ... Special Guest Appearance |
| Sinéad Dolan | ... Special Guest Appearance |
| Paul Ferriter | ... Special Guest Appearance |
| Larry Fessenden | ... Kissing Man |
| Sarah Fiol | ... Special Guest Appearance |
| Tanya Gingerich | ... Special Guest Appearance |
| Paul Graham | ... Special Guest Appearance |
| Henry Griffin | ... Special Guest Appearance |
| India Reed Kotis | ... Special Guest Appearance |
| Ayun Halliday | ... Special Guest Appearance |
| Greg Kotis | ... Special Guest Appearance |
| Barry Manasch | ... Special Guest Appearance |
| Philip McKenney | ... Special Guest Appearance |
| Anne Nixon | ... Special Guest Appearance |
| Colin Puth | ... Special Guest Appearance |
| Charles Renfro | ... Special Guest Appearance |
| Giancarlo Roma | ... Special Guest Appearance |
| Thomas Roma | ... Special Guest Appearance |
| Kelly Millicent Sebastian | ... Special Guest Appearance |
