| Richard Harris | ... Prescott Roe |
| Sheila Tousey | ... Awbonnie / Ghost |
| Alan Bates | ... Eamon McCree |
| River Phoenix | ... Talbot Roe |
| Dermot Mulroney | ... Reeves McCree |
| Jeri Arredondo | ... Velada McCree |
| Tantoo Cardinal | ... Silent Tongue |
| Bill Irwin | ... Comic |
| David Shiner | ... Straight Man |
|
| Medicine Show Band -- The Red Clay Ramblers |
| Tommy Thompson | ... Medicine Show Band Performer |
| Jack Herrick | ... Medicine Show Band Performer |
| Bland Simpson | ... Medicine Show Band Performer |
| Clay Buckner | ... Medicine Show Band Performer |
| Chris Frank | ... Medicine Show Band Performer |
|
| Arturo Gil | ... Little Person Acrobat #1 |
| Joseph Griffo | ... Little Person Acrobat #2 |
| Billy Beck | ... Petrified Man |
| Phillip Attmore | ... Boy Tap Dancer |
| Al Lujan | ... Kiowa Drummer |
| Devino Tricoche | ... Fire-Eater |
| April Tatro | ... Contortionist |
| Tim Carroll | ... Stage Coach Driver |
| Nicholas Ortiz Y Pino | ... Young Reeves |
| Robert Harnsberger | ... Buffalo Hunter |
| Fred Maio | ... Owner |
| David E. Wynne | ... Easterner |
| Sky Fabin | ... Easterner |
| Leslie Flemming | ... Easterner |
| Jill Momaday | ... Prostitute |
| Lynn Davis | ... Prairie Girl |
| Tim Scott | ... The Lone Man |
